abstract：PURPOSE:To compare the efficacy and visual outcomes after femtosecond laser small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) in correcting high myopia. METHODS:This prospective, randomized study included patients who underwent SMILE or FS-LASIK for the ...

journal_title：Acta ophthalmologica

authors： Qian Y,Chen X,Naidu RK,Zhou X

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Ocular and brain microcirculation share embryological and histological similarities. The retinal vascular fractal dimension (FD) is a marker of retinal vascular complexity of the vascular tree. The purpose of this study was to explore the relationship between cerebral blood flow (CBF), retinal vascular FD and o...

journal_title：Acta ophthalmologica

authors： Nadal J,Deverdun J,de Champfleur NM,Carriere I,Creuzot-Garcher C,Delcourt C,Chiquet C,Kawasaki R,Villain M,Ritchie K,Le Bars E,Daien V

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To explore the efficacy of selective laser trabeculoplasty (SLT) within eyes with exfoliative glaucoma and history of prior argon laser trabeculoplasty (ALT). METHODS:A single-centre trial consisting of 47 patients (47 eyes) with uncontrolled exfoliative glaucoma. The main outcome measure was intraocular press...

journal_title：Acta ophthalmologica

authors： Ilveskoski L,Taipale C,Tuuminen R

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Photoscreening assesses risk factors for amblyopia, as an alternative to measurement of visual acuity (VA) to detect amblyopia, on the premise that its early correction could prevent development of amblyopia. We studied implementations of Plusoptix photoscreening in existing population-based screening in Flande...

journal_title：Acta ophthalmologica

authors： Bostamzad P,Horwood AM,Schalij-Delfos NE,Boelaert K,de Koning HJ,Simonsz HJ

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Galectin-1 regulates endothelial cell function and promotes angiogenesis. We investigated the hypothesis that galectin-1 may be involved in the pathogenesis of proliferative diabetic retinopathy (PDR). METHODS:Vitreous samples from 36 PDR and 20 nondiabetic patients, epiretinal fibrovascular membranes from 13 ...

journal_title：Acta ophthalmologica

authors： Abu El-Asrar AM,Ahmad A,Allegaert E,Siddiquei MM,Alam K,Gikandi PW,De Hertogh G,Opdenakker G

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To determine the myopia prevalence in Hong Kong Chinese children and their parents. METHODS:It was a population-based cross-sectional study. A total of 4257 children aged 6-8 years, and 5880 parents were recruited in the Hong Kong Children Eye Study. Cycloplegic autorefraction was measured for children; and no...

journal_title：Acta ophthalmologica

authors： Yam JC,Tang SM,Kam KW,Chen LJ,Yu M,Law AK,Yip BH,Wang YM,Cheung CYL,Ng DSC,Young AL,Tham CC,Pang CP

更新日期：2020-01-24 00:00:00

abstract：PURPOSE:Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering o...

journal_title：Acta ophthalmologica

authors： Prokosch V,Brockhaus K,Anders F,Liu H,Mercieca K,Gericke A,Melkonyan H,Thanos S

更新日期：2019-12-29 00:00:00

abstract：:Ziv-aflibercept (Zaltrap® ), a recombinant fusion protein that binds diffusible vascular endothelial growth factor (VEGF), is approved for the treatment of metastatic colorectal carcinoma. Its molecular structure is the same as aflibercept (Eylea® ), thus making it an attractive option for the off-label treatment of c...

journal_title：Acta ophthalmologica

authors： Mansour AM,Stewart MW,Farah ME,Mansour HA,Chhablani J

更新日期：2019-12-20 00:00:00

abstract：PURPOSE:To examine retinal vascular changes in the peripapillary and macular areas in patients with pituitary adenoma (PA) using optical coherence tomography angiography (OCTA). METHODS:Cross-sectional, retrospective study of 17 consecutive PA patients and 16 healthy subjects. All patients underwent a neuro-ophthalmol...

journal_title：Acta ophthalmologica

authors： Dallorto L,Lavia C,Jeannerot AL,Shor N,Jublanc C,Boch AL,Bodaghi B,Tadayoni R,Touitou V,Bonnin S

更新日期：2019-12-06 00:00:00

abstract：PURPOSE:We investigated the natural course of the intraretinal hyperreflective (IRH) sign after macular haemorrhage (MHE) absorption in eyes with pathologic myopia. METHODS:This prospective observational cohort study evaluated 28 patients with pathologic myopia and MHE. The eyes were categorized into IRH and non-IRH s...

journal_title：Acta ophthalmologica

authors： Hung KC,Wang SW,Hsia Y,Chen MS,Tsai CY,Ho TC

更新日期：2019-12-06 00:00:00

abstract：PURPOSE:To describe the annual incidence rate of keratoconus in Denmark 1995-2015 and prevalence of keratoconus in the National Danish Patient Register 1977-2015. METHODS:All patients diagnosed with keratoconus in the National Danish Patient Register 1977-2015 were included in the study. The annual incidence rates and...

journal_title：Acta ophthalmologica

authors： Bak-Nielsen S,Ramlau-Hansen CH,Ivarsen A,Plana-Ripoll O,Hjortdal J

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To analyse the postoperative foveal avascular zone (FAZ) area, superficial vessel density (SVD) and deep vessel density (DVD) and their correlation with functional (best-corrected visual acuity, BCVA) and anatomical outcomes (foveal macular thickness, FMT) after surgery for rhegmatogenous retinal detachment (RR...

journal_title：Acta ophthalmologica

authors： Bonfiglio V,Ortisi E,Scollo D,Reibaldi M,Russo A,Pizzo A,Faro G,Macchi I,Fallico M,Toro MD,Rejdak R,Nowomiejska K,Toto L,Rinaldi M,Cillino S,Avitabile T,Longo A

更新日期：2019-11-26 00:00:00

abstract：PURPOSE:To examine visual acuity, refraction and ocular status before, during and after hyperbaric oxygen therapy (HBOT). METHODS:Twenty-nine patients underwent 40 standard protocol HBOT treatments. In all subjects, refraction and best corrected visual acuity were measured at baseline and after ten, 20, 30 and 40 trea...

journal_title：Acta ophthalmologica

authors： Riedl P,Škiljić D,Arnell P,Wannholt R,Zetterberg M,Andersson Grönlund M

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To examine preoperative anti-inflammatory treatment on recovery from cataract surgery in eyes of diabetic patients. METHODS:A Prospective randomized clinical trial. One hundred and three eyes of 103 patients with diabetes undergoing routine cataract surgery were randomized (1:1) not to receive any preoperative...

journal_title：Acta ophthalmologica

authors： Danni R,Viljanen A,Aaronson A,Tuuminen R

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To compare the efficacy and safety of collagen matrix implant (Ologen® ; OLO) with mitomycin C (MMC) in phacotrabeculectomy. METHODS:Prospective, single-centre, nonblinded, randomized controlled trial. A total of 53 eyes of 45 patients were enrolled in the study protocol with 27 eyes randomly assigned to OLO a...

journal_title：Acta ophthalmologica

authors： Wlaź A,Wilkos-Kuc A,Rozegnał-Madej A,Żarnowski T

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To investigate whether exposure to antazoline-naphazoline eye drops in the first trimester of pregnancy was associated with an increased risk of malformations in humans. METHODS:All women giving live birth between 1997 and 2011 in Denmark were included in this nationwide cohort study. All women redeeming at le...

journal_title：Acta ophthalmologica

authors： Thomseth V,Cejvanovic V,Jimenez-Solem E,Poulsen HE,Utheim TP,Andersen JT

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To employ ultrahigh-resolution (UHR) optical coherence tomography (OCT) for investigation of the early wound healing process in corneal epithelium. METHODS:A custom-built UHR-OCT system assessed epithelial healing in human keratoconic cornea after epi-off crosslinking (CXL) procedure and a wound healing model ...

journal_title：Acta ophthalmologica

authors： Pantalon A,Pfister M,Aranha Dos Santos V,Sapeta S,Unterhuber A,Pircher N,Schmidinger G,Garhöfer G,Schmidl D,Schmetterer L,Werkmeister RM

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:We report the epidemiology, findings, treatment, long-term outcome and use of resources for eye injuries caused by toy guns in southern Finland. METHODS:All new patients injured by toy guns in one year (2011-2012) and treated at Helsinki University Eye Hospital were included. Follow-ups occurred at 3 months an...

journal_title：Acta ophthalmologica

authors： Haavisto AK,Sahraravand A,Puska P,Leivo T

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To assess the effect of donor tissue diameter in Descemet Membrane Endothelial Keratoplasty (DMEK) on postoperative endothelial cell density (ECD) mainly in Fuchs Endothelial Corneal Dystrophy (FECD) patients. METHODS:Retrospective review of 693 consecutive DMEK surgeries from the prospective Cologne DMEK data...

journal_title：Acta ophthalmologica

authors： Schrittenlocher S,Bachmann B,Cursiefen C

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To investigate the prevalence of potential age-related eye conditions in elderly who are assisted by home healthcare nurses. The number of referrals to the general practitioner (GP), feasibility of screening and associations between vision loss and health outcomes were also studied. METHODS:Cross-sectional stu...

journal_title：Acta ophthalmologica

authors： van Nispen R,van der Aa H,Timmermans F,Meijer N,Koster N,de Blok J,Keunen J,van Rens G

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:Choroideremia is a currently incurable X-linked recessive retinal degeneration that leads to blindness. Gene therapy approaches to date target the outer retinal layers. However, the choroideremia (CHM) gene is expressed in all retinal layers, and a previous study on a small cohort of choroideremia patients sugg...

journal_title：Acta ophthalmologica

authors： Fu DJ,Xue K,Jolly JK,MacLaren RE

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To evaluate the trends and variations in global health burden of glaucoma by year, age and sex, region and socio-economic status, using disability-adjusted life years (DALYs). METHOD:The DALY numbers, crude DALY rate and age-standardized DALY rate globally and in each country were obtained the GBD 2015 study d...

journal_title：Acta ophthalmologica

authors： Wang W,He M,Li Z,Huang W

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To investigate the frequency of primary angle closure (PAC) and primary angle closure glaucoma (PACG) in patients with retinal vein occlusion (RVO) based on a hospital population. METHODS:A total of 375 consecutive cases newly diagnosed with RVO by fluorescein fundus angiography at a single eye centre in Pekin...

journal_title：Acta ophthalmologica

authors： Xu K,Wu L,Ma Z,Liu Y,Qian F

更新日期：2019-05-01 00:00:00

abstract：:Corneal refractive surgery disrupts corneal integrity and reduces biomechanical stability in consequence of the beneficial refractive alteration. The minimal invasive cap-based refractive procedure, small-incision lenticule extraction (SMILE), has been proposed to affect corneal integrity less than flap-based procedur...

journal_title：Acta ophthalmologica

authors： Raevdal P,Grauslund J,Vestergaard AH

更新日期：2019-03-01 00:00:00

abstract：:To review binocular and accommodative disorders documented after corneal or intraocular refractive surgery, in normal healthy prepresbyopic patients. A bibliographic revision was performed; it included works published before 1st July 2017 where accommodation and/or binocularity was assessed following any type of refra...

journal_title：Acta ophthalmologica

authors： García-Montero M,Albarrán Diego C,Garzón-Jiménez N,Pérez-Cambrodí RJ,López-Artero E,Ondategui-Parra JC

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To investigate the correlation between retinal vessel oxygen saturation and mixed venous oxygen saturation (SvO2-mixed ) and cardiac output (CO). METHODS:Retinal arterial (SaO2-retinal ) and venous (SvO2-retinal ) oxygen saturation were measured non-invasively with dual-wavelength retinal oximetry in subjects ...

journal_title：Acta ophthalmologica

authors： Van Keer K,Van Keer J,Barbosa Breda J,Nassiri V,Van Cleemput J,Abegão Pinto L,Stalmans I,Vandewalle E

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To analyse intraocular cytokine levels and prevalence of intraocular antiretinal antibodies (ARAs) in patients with retinitis pigmentosa (RP), age-related macular degeneration (AMD), glaucoma and cataract, and correlate the results to clinical manifestations. METHODS:We collected intraocular fluid samples from...

journal_title：Acta ophthalmologica

authors： Ten Berge JC,Fazil Z,van den Born I,Wolfs RCW,Schreurs MWJ,Dik WA,Rothova A

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To examine the role of systemic medication on the risk of pseudophakic cystoid macular edema (PCME) following uneventful cataract surgery. METHODS:A total of 269 eyes undergoing routine cataract surgery. Spectral-domain optical coherence tomography imaging was conducted before surgery and at 28 days. Informati...

journal_title：Acta ophthalmologica

authors： Danni R,Taipale C,Holmström EJ,Ilveskoski L,Tuuminen R

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Tissue inhibitor of metalloproteinase (TIMP) is known to play a role in age-related macular degeneration (AMD). We wished to investigate alterations in different late stages of AMD: neovascular AMD and geographic atrophy (GA). METHODS:This was a prospective case-control study. A total of 125 participants were ...

journal_title：Acta ophthalmologica

authors： Krogh Nielsen M,Subhi Y,Rue Molbech C,Nilsson LL,Nissen MH,Sørensen TL

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects. METHODS:Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS e...

journal_title：Acta ophthalmologica

authors： Klefter ON,Kofoed PK,Munch IC,Larsen M

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To explore the association between retinal vein occlusion (RVO) and incident cancer. METHODS:All Danish citizens with a first-time diagnosis of RVO and no previous diagnosis of cancer in the period from 1 January 2004 to 31 December 2014 were included. Five likewise cancer-free, age- and gender-matched control...

journal_title：Acta ophthalmologica

authors： Toft-Petersen AP,Muttuvelu DV,Heegaard S,Torp-Pedersen C

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Study purpose was to investigate the effects of bariatric surgery on intraocular pressure (IOP) and other ophthalmic parameters in a prospective observational follow-up study. METHODS:Ophthalmic examination was performed on 22 obese women before and 6 months after bariatric surgery. A control group of 15 non-o...

journal_title：Acta ophthalmologica

authors： Viljanen A,Hannukainen JC,Soinio M,Karlsson HK,Salminen P,Nuutila P,Vesti E

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Lacrimal gland tumours constitute a wide spectrum of neoplastic lesions that are histologically similar to tumours of the salivary gland. In the salivary gland, pleomorphic adenoma (PA) is frequently characterized by recurrent chromosomal rearrangements of the PLAG1 and HMGA2 genes, a genetic feature retained i...

journal_title：Acta ophthalmologica

authors： Andreasen S,von Holstein SL,Homøe P,Heegaard S

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:Posterior capsule opacification (PCO) occurs as a common complication after cataract surgery. Erlotinib is an inhibitor of the epidermal growth factor-Receptor and reduces critical cellular events leading to PCO. In this in vitro study, Erlotinib-modified intraocular lenses (IOLs) employed as a drug delivery de...

journal_title：Acta ophthalmologica

authors： Wertheimer C,Kueres A,Siedlecki J,Braun C,Kassumeh S,Wolf A,Mayer W,Priglinger C,Priglinger S,Eibl-Lindner K

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical ...

journal_title：Acta ophthalmologica

authors： Gerendas BS,Kroisamer JS,Buehl W,Rezar-Dreindl SM,Eibenberger KM,Pablik E,Schmidt-Erfurth U,Sacu S

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To investigate flow area changes measured using optical coherence tomography angiography (OCTA; RTVue XR Avanti® ) in patients with retinitis pigmentosa (RP) with preserved visual acuity (VA). METHODS:This was an age- and refraction-matched case-control study. Consecutive patients with a best-corrected visual ...

journal_title：Acta ophthalmologica

authors： Takagi S,Hirami Y,Takahashi M,Fujihara M,Mandai M,Miyakoshi C,Tomita G,Kurimoto Y

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To study presenting characteristics and prevalence of polypoidal choroidal vasculopathy (PCV) in Scandinavian Caucasians with treatment-naïve exudative age-related macular degeneration (AMD). METHODS:We reviewed all patients referred in year 2014 and diagnosed using fundus examination, optical coherence tomogr...

journal_title：Acta ophthalmologica

authors： Lorentzen TD,Subhi Y,Sørensen TL

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To describe the different clinical presentations of periocular molluscum contagiosum (MC) lesions and their epidemiological, clinical and histopathological features. METHODS:Medical records and histopathological sections of all cases of periocular MC treated at the oculoplastic clinic of the Goldschleger Eye I...

journal_title：Acta ophthalmologica

authors： Rosner M,Zloto O

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To investigate the cerebrospinal fluid (CSF) dynamics along the entire optic nerve (ON) in patients with normal-tension glaucoma (NTG). METHODS:Retrospective analysis of computed tomographic (CT) cisternographies in Caucasian patients with NTG. Fifty-six patients (99 of 112 eyes) fulfilled the diagnostic crite...

journal_title：Acta ophthalmologica

authors： Pircher A,Montali M,Wostyn P,Pircher J,Berberat J,Remonda L,Killer HE

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:We aimed to determine whether intravitreal dexamethasone as an adjuvant to intravitreal antibiotics is beneficial in the treatment of suspected bacterial endophthalmitis after cataract surgery. METHODS:Randomized, placebo-controlled superiority trial in three tertiary referral centres in the Netherlands. Patie...

journal_title：Acta ophthalmologica

authors： Manning S,Ugahary LC,Lindstedt EW,Wubbels RJ,van Dissel JT,Jansen JTG,Gan I,van Goor AT,Bennebroek CA,van der Werf DJ,Ossewaarde-van Norel A,Mayland Nielsen CC,Tilanus M,van den Biesen PR,Schellekens PA,La Heij E,Faridpoo

更新日期：2018-06-01 00:00:00